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Normotim

Dicover how NORMOTIM improves everyday life

Lithium Ascorbate

Next-gen lithium supports mood and brain functions

12 times less toxic than commonly used lithium carbonate, and the effective therapeutic dosage is 10 times lower [1].

Lithium

Lithium acts as a mood stabilizer, reducing anxiety and symptoms of depression [2]. It also prevents the development of acute stress by blocking adrenaline and noradrenaline. Additionally, it has a brain-boosting effect, enhancing concentration and improving memory.

Vitamin C

A natural antioxidant, it empowers lithium’s efficacy. It also contributes to synthesizing the "happy hormone" serotonin [3,4,5], affects mood and cognitive function [5,6,7], and protects the brain against oxidative stress [8].

[1] Lithium Ascorbate as a Promising Neuroprotector: Fundamental and Experimental Studies of an Organic Lithium Salt. Ivan Yu. Torshin, Olga A. Gromova,Konstantin S. Ostrenko, Marina V. Filimonova, Irina V. Gogoleva, Vladimir I. Demidov, and Alla G. Kalacheva. Molecules. 2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000476/

[2] Comparing measurements of lithium treatment efficacy in people with bipolar disorder: systematic review and meta-analysis. Andrea Ulrichsen, Elliot Hampsey, Rosie H. Taylor, Romayne Gadelrab, Rebecca Strawbridge, and Allan H. Young. British Journal of Psychiatry Open. 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228238/

[3] Effect of Diet on Depression: A Review of Nutritional Solutions. Hananeh Ahmadnia, Hassan Bahrami, Soraya Mohamadzadeh. World Nutrition. 2023. https://www.researchgate.net/publication/369718030_Effect_of_Diet_on_Depression_A_Review_of_Nutritional_Solutions

[4] The role of ascorbic acid in the oxidation of tryptophan to 5-hydroxytryptophan. Jack R. Cooper. Annals of the New York Academy of Sciences. 2006. https://www.researchgate.net/publication/228047757_The_role_of_ascorbic_acid_in_the_oxidation_of_tryptophan_to_5-hydroxytryptophan

[5] From antioxidant to neuromodulator: The role of ascorbate in the management of major depression disorder. Nuno R. Ferreira, Carla Vitorino, Ana Fortuna. Biochemical Pharmacology. 2022. https://www.sciencedirect.com/science/article/pii/S000629522200394X

[6] Vitamin C supplementation promotes mental vitality in healthy young adults: results from a cross-sectional analysis and a randomized, double-blind, placebo-controlled trial. Minju Sim, Sehwa Hong, Sungwoong Jung, Jin-Soo Kim, Young-Tae Goo, Woo Young Chun. European Journal of Nutrition. 2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783887/

[7] Vitamin C Status and Cognitive Function: A Systematic Review. Nikolaj Travica, Karin Ried, Avni Sali, Andrew Scholey, Irene Hudson, and Andrew Pipingas. Nutrients. 2017. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622720/

[8] The role of vitamin C in stress-related disorders. Bettina Moritz, Ariana E. Schmitz, Ana Lúcia S. Rodrigues, Alcir L. Dafre, Mauricio P. Cunha. The Journal of Nutritional Biochemistry. 2020. https://www.sciencedirect.com/science/article/pii/S0955286320304915

Vitamin C

Forms an effective combo with lithium

A natural antioxidant, it empowers lithium’s efficacy. It also contributes to synthesizing neurotransmitters, affects mood and cognitive function[2], and protects the brain against oxidative stress[3].

[2] Ivan Torshin, Olga Gromova, Konstantin Ostrenko, 'Lithium Ascorbate as a Promising Neuroprotector: Fundamental and Experimental Studies of an Organic Lithium Salt' (March, 2022), Molecules: a journal of synthetic chemistry and natural product chemistry.

[3] Ashor AW, Brown R, Keenan PD, Willis ND, Siervo M, Mathers JC. Limited evidence for a beneficial effect of vitamin C supplementation on biomarkers of cardiovascular diseases: an umbrella review of systematic reviews and meta-analyses. (January, 2019), Nutrition research.

Vitamin B6

Aids cognitive functions and synthesis of serotonin

It supports brain function and synthesizes neurotransmitters that regulate mood, such as serotonin, dopamine, and GABA [1], reducing anxiety and depression [2,3]

[1] Vitamin B6 and Its Role in Cell Metabolism and Physiology. Parra M, Stahl S, Hellmann H. Cells. 2018. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071262/

[2] High‐dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression. David T. Field, Rebekah O. Cracknell, Jessica R. Eastwood, Peter Scarfe, Claire M. Williams, Ying Zheng, and Teresa Tavassoli, Hum Psychopharmacol. 2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787829/

[3] A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and ‘At-Risk’ Individuals. Lauren M Young, Andrew Pipingas, David J White, Sarah Gauci, and Andrew Scholey. Nutrients. 2019. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770181/

Vitamin B1

Improves memory, maintains energy

It is essential for brain function and synthesizing the neurotransmitter acetylcholine, which is involved in memory and mood regulation [1, 2]. B1 helps to convert nutrients into energy [3], keeping your high performance level.

[1] Vitamin B1 (thiamine) and dementia. Gary E. Gibson, Joseph A. Hirsch, Pasquale Fonzetti, Barry D. Jordon, Rosanna T. Cirio, and Jessica Elder. Annals of the New York Academy of Sciences. 2016. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846521/

[2] The importance of thiamine (vitamin B1) in humans. Małgorzata Mrowicka, Jerzy Mrowicki,, Grzegorz Dragan, and Ireneusz Majsterek. Bioscience Reports. 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568373/

[3] Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence. Anne-Laure Tardy, Etienne Pouteau, Daniel Marquez,Cansu Yilmaz and Andrew Schole. Nutrients. 2020. https://www.mdpi.com/2072-6643/12/1/228

Lithium Ascorbate

Dicover how Lithium Ascorbate improves everyday life.

optimal daily dosage

Lithium is essential for our mental well-being. Our body requires 0.7 mg of lithium every day; without it, the risk of mental conditions increases. The pill offers 1 mg of safe and highly effective lithium, supporting mood and mental health.

Powerful Neuroprotective Effect

Lithium & ascorbic acid together create a combo nootropic effect, which boosts your cognitive abilities to maintain brain health.

Increases brain-derived neurotrophic factor (BDNF) by 9%. It is a neurotrophic agent — a protein crucial for thinking, memory, neuroplasticity, and neuronal survival. It promotes connections between neurons, boosting brain neuroplasticity and cognitive function.

Lithium elevates the levels of neurotrophic factors including Brain-Derived Neurotrophic Factor (BDNF), Nerve Growth Factor (NGF), and Glial cell line-derived Neurotrophic Factor (GDNF). Both are known to contribute to increased neuronal survival and neuroplasticity, enhancing the regenerative capacity and formation of new synaptic connections among dopaminergic, cholinergic, and serotonergic neurons within the central nervous system.

Improves memory by lowering levels of anxiety, depression, and chronic stress. Improves visual memory by 83%, auditory-verbal memory by 98%, and muscle memory by 83%.

Reduces alcohol-induced neuron death by half. When the brain is exposed to prolonged alcohol toxicity, Lithium Ascorbate halves neuron death (18% vs. 36%) compared to without it.

Highly Effective Even in Low Doses

A new generation lithium salt combines two powerful active ingredients — lithium and vitamin C — in a single molecule
It is 12 times safer than lithium carbonate
It is 10 times more effective in low doses compared to lithium carbonate

Mood Stabilization

Lithium Ascorbate supplement increases the level of the "happiness hormone"

As the result, it decreases anxiety by 35% on the Hospital Anxiety and Depression Scale (HADS).

Works as an antidepressant, lowering the level of depression by 39% on Hospital Anxiety and Depression Scale (HADS) over 60 days.

blocking the stress hormones

Blocks secretion of stress hormones (adrenaline, norepinephrine, and cortisol), which prevents acute stress from becoming chronic.

By doing this, Lithium ascorbate allows for adequate and logical decisions to be made even under acute stress (the part of the brain that controls emotions happens to be the older part of the brain - it can send signals directly to the body, avoiding the frontal lobe, which controls logical thinking, creating the “fight or flight” response).

Balanced Mood

Increases levels of serotonin (the happy hormone).
Works as an antidepressant, lowering the level of depression by 39% on Hospital Anxiety and Depression Scale (HADS) over a 60-day period.
Prevents glutamate stress, which leads to anxiety disorders.
Decreases anxiety by 35% on the Hospital Anxiety and Depression Scale (HADS).
Maintains emotional stability, reduces mood swings
Stabilizes circadian rhythms, enhances sleep patterns, crucial for deeper and more restful sleep

Brain Boost & Neuroprotection

Increases brain-derived neurotrophic factor (BDNF) by 9% — a neurotrophic agent, a protein that is crucial for thinking, memory, neuroplasticity, and neuronal survival. It also exhibits antidepressant effects.
Lithium & ascorbic acid together create a combo nootropic effect, which boosts your cognitive abilities.
Improves memory by lowering levels of anxiety, depression, and chronic stress. Improves visual memory by 83%, auditory-verbal memory by 98%, and muscle memory by 83%
The effect of lithium ascorbate is enhanced by Vitamins B1 and B6, which improve cognitive function and nourish the nervous system.
Provides neuroprotection, which prevents the onset of cognitive disorders related to aging, such as Alzheimer’s and Dementia.
Reducing Alcohol-Induced Neuron Death by Half. When the brain is exposed to prolonged alcohol toxicity, Lithium Ascorbate halves neuron death (6% vs. 18%) compared to without it.

Antiage Impact

Increases VEGF (Vascular Endothelial Growth Factor), an essential component in the regeneration of blood vessels after stroke and heart attack
Improves visual memory by 83%, auditory-verbal memory by 98%, and muscle memory by 83%
Provides neuroprotection, which prevents the onset of cognitive disorders related to aging, such as Alzheimer’s and Dementia
Improves concentration and information retention
The effect of lithium ascorbate is enhanced by Vitamins B1 and B6, which improve cognitive function and nourish the nervous system
Helps to maintain bone mineral density

Safety

12 times less toxic than other Lithium compounds.
The effective dose is 10 times lower than in the case of other Lithium compounds.
Lithium levels are safe and approved for over-the-counter use.
Formula is backed by 3 US patents.
No known or expected side effects.

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