About Lithium Ascorbate

Lithium Ascorbate

Next-gen lithium supports mood and brain functions

12 times less toxic than commonly used lithium carbonate, and the effective therapeutic dosage is 10 times lower [1].

Lithium

Lithium acts as a mood stabilizer, reducing anxiety and symptoms of depression [2]. It also prevents the development of acute stress by blocking adrenaline and noradrenaline. Additionally, it has a brain-boosting effect, enhancing concentration and improving memory.

Vitamin C

A natural antioxidant, it empowers lithium’s efficacy. It also contributes to synthesizing the "happy hormone" serotonin [3,4,5], affects mood and cognitive function [5,6,7], and protects the brain against oxidative stress [8].

[1] Lithium Ascorbate as a Promising Neuroprotector: Fundamental and Experimental Studies of an Organic Lithium Salt. Ivan Yu. Torshin, Olga A. Gromova,Konstantin S. Ostrenko, Marina V. Filimonova, Irina V. Gogoleva, Vladimir I. Demidov, and Alla G. Kalacheva. Molecules. 2022.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000476/ 

[2] Comparing measurements of lithium treatment efficacy in people with bipolar disorder: systematic review and meta-analysis. Andrea Ulrichsen, Elliot Hampsey, Rosie H. Taylor, Romayne Gadelrab, Rebecca Strawbridge, and Allan H. Young. British Journal of Psychiatry Open. 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228238/ 

[3] Effect of Diet on Depression: A Review of Nutritional Solutions. Hananeh Ahmadnia, Hassan Bahrami, Soraya Mohamadzadeh. World Nutrition. 2023. https://www.researchgate.net/publication/369718030_Effect_of_Diet_on_Depression_A_Review_of_Nutritional_Solutions 

[4] The role of ascorbic acid in the oxidation of tryptophan to 5-hydroxytryptophan. Jack R. Cooper. Annals of the New York Academy of Sciences. 2006. https://www.researchgate.net/publication/228047757_The_role_of_ascorbic_acid_in_the_oxidation_of_tryptophan_to_5-hydroxytryptophan 

[5] From antioxidant to neuromodulator: The role of ascorbate in the management of major depression disorder. Nuno R. Ferreira, Carla Vitorino, Ana Fortuna. Biochemical Pharmacology. 2022. https://www.sciencedirect.com/science/article/pii/S000629522200394X 

[6] Vitamin C supplementation promotes mental vitality in healthy young adults: results from a cross-sectional analysis and a randomized, double-blind, placebo-controlled trial. Minju Sim, Sehwa Hong, Sungwoong Jung, Jin-Soo Kim, Young-Tae Goo, Woo Young Chun. European Journal of Nutrition. 2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783887/ 

[7] Vitamin C Status and Cognitive Function: A Systematic Review. Nikolaj Travica, Karin Ried, Avni Sali, Andrew Scholey, Irene Hudson, and Andrew Pipingas. Nutrients. 2017. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622720/ 

[8] The role of vitamin C in stress-related disorders. Bettina Moritz, Ariana E. Schmitz, Ana Lúcia S. Rodrigues, Alcir L. Dafre, Mauricio P. Cunha. The Journal of Nutritional Biochemistry. 2020. https://www.sciencedirect.com/science/article/pii/S0955286320304915 

Vitamin C

Forms an effective combo with lithium

A natural antioxidant, it empowers lithium’s efficacy. It also contributes to synthesizing neurotransmitters, affects mood and cognitive function[2], and protects the brain against oxidative stress[3].

[2] Ivan Torshin, Olga Gromova, Konstantin Ostrenko, 'Lithium Ascorbate as a Promising Neuroprotector: Fundamental and Experimental Studies of an Organic Lithium Salt' (March, 2022), Molecules: a journal of synthetic chemistry and natural product chemistry.

[3] Ashor AW, Brown R, Keenan PD, Willis ND, Siervo M, Mathers JC. Limited evidence for a beneficial effect of vitamin C supplementation on biomarkers of cardiovascular diseases: an umbrella review of systematic reviews and meta-analyses. (January, 2019), Nutrition research.

Vitamin B6

Aids cognitive functions and synthesis of serotonin

It supports brain function and synthesizes neurotransmitters that regulate mood, such as serotonin, dopamine, and GABA [1], reducing anxiety and depression [2,3]

[1] Vitamin B6 and Its Role in Cell Metabolism and Physiology. Parra M, Stahl S, Hellmann H. Cells. 2018. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071262/ 

[2] High‐dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression. David T. Field, Rebekah O. Cracknell, Jessica R. Eastwood, Peter Scarfe, Claire M. Williams, Ying Zheng, and Teresa Tavassoli, Hum Psychopharmacol. 2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787829/

[3] A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and ‘At-Risk’ Individuals. Lauren M Young, Andrew Pipingas, David J White, Sarah Gauci, and Andrew Scholey. Nutrients. 2019. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770181/ 

Vitamin B1

Improves memory, maintains energy

It is essential for brain function and synthesizing the neurotransmitter acetylcholine, which is involved in memory and mood regulation [1, 2]. B1 helps to convert nutrients into energy [3], keeping your high performance level.

[1] Vitamin B1 (thiamine) and dementia. Gary E. Gibson, Joseph A. Hirsch, Pasquale Fonzetti, Barry D. Jordon, Rosanna T. Cirio, and Jessica Elder. Annals of the New York Academy of Sciences. 2016. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846521/

[2] The importance of thiamine (vitamin B1) in humans. Małgorzata Mrowicka, Jerzy Mrowicki,, Grzegorz Dragan, and Ireneusz Majsterek. Bioscience Reports. 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568373/ 

[3] Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence. Anne-Laure Tardy, Etienne Pouteau, Daniel Marquez,Cansu Yilmaz and Andrew Schole. Nutrients. 2020. https://www.mdpi.com/2072-6643/12/1/228 

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Dive into the science of lithium ascorbate with our detailed infographic. Discover its benefits, impact on mental health, and the research-backed data that makes Normotim a breakthrough in well-being.